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Epidemic dynamics: Stochastic spreading and spatial control

Spatial map of a local epidemic containment strategy
Cooperative effect of spatially targeted containment (Bittihn, Hupe, Isensee, Golestanian, EClinicalMedicine 2021).

Epidemic models often ignore spatial structure and stochastic fluctuations — yet these features decide whether local outbreaks grow into pandemics. Applying tools from nonlinear dynamics and stochastic spatial systems, we found that population subdivision reshapes outbreak probabilities in ways deterministic models miss.

Building on this, we showed that geographically targeted restrictions can suppress an epidemic at least as effectively as uniform measures while requiring far fewer total restrictions, through a cooperative buffering effect — providing quantitative support for adaptive, localised response strategies. Both studies were released together with open-source simulation and analysis code.

Selected publications

Local measures enable COVID-19 containment with fewer restrictions due to cooperative effects

P. Bittihn, L. Hupe, J. Isensee, R. Golestanian

EClinicalMedicine (The Lancet) 32, 100718 (2021)

Stochastic effects on the dynamics of an epidemic due to population subdivision

P. Bittihn, R. Golestanian

Chaos 30, 101102 (2020)