Publications

A minimal mechanically consistent model of smoothly dividing disk-shaped cells

L. Hupe, Y. G. Pollack, J. Isensee, A. Amiri, R. Golestanian, P. Bittihn

npj Systems Biology and Applications 12, 91

Phase separation in a mixture of proliferating and motile active matter

L. Hupe, J. M. Materska, D. Zwicker, R. Golestanian, B. Waclaw, P. Bittihn

Physical Review Research 8, L022012

Prediction and control of geometry-induced nematic order in growing multicellular systems

L. Hupe, J. Isensee, R. Golestanian, P. Bittihn

Order and shape dependence of mechanical relaxation in proliferating active matter

J. Isensee, L. Hupe, P. Bittihn

Sensitive particle shape dependence of growth-induced mesoscale nematic structure

J. Isensee, P. Bittihn

Soft Matter 21, 4233

3D multiscale shape analysis of nuclei and in vivo elastic stress sensors allows force inference

A. Jurado, J. Isensee, A. Hofemeier, L. J. Krüger, R. Wittkowski, R. Golestanian, P. Bittihn, T. Betz

Biophysical Journal 124, 2784

Orientational lineage memory and mechanical ordering during diffusion-limited growth

I.-M. Sarris, R. Golestanian, P. Bittihn

Motility-induced mixing transition in exponentially growing multicellular spheroids

T. Sunkel, L. Hupe, P. Bittihn

Communications Physics 8, 179

Dimensionality and confinement reshape competition in cellular renewing active matter

P. Zimmer, P. Bittihn, Y. G. Pollack

Collective self-caging of active filaments in virtual confinement

M. Kurjahn, L. Abbaspour, F. Papenfuß, P. Bittihn, R. Golestanian, B. Mahault, S. Karpitschka

Nature Communications 15, 9122

Isovolumetric dividing active matter

S. R. Lish, L. Hupe, R. Golestanian, P. Bittihn

Dynamical model of antibiotic responses linking expression of resistance to metabolism explains emergence of heterogeneity during drug exposures

M. Stevanovic, J. P. Teuber Carvalho, P. Bittihn, D. Schultz

Physical Biology 21, 036002

Stress anisotropy in confined populations of growing rods

J. Isensee, L. Hupe, R. Golestanian, P. Bittihn

Journal of the Royal Society Interface 19, 20220512

A competitive advantage through fast dead matter elimination in confined cellular aggregates

Y. G. Pollack, P. Bittihn, R. Golestanian

New Journal of Physics 24, 073003

Nutrient gradients mediate complex colony-level antibiotic responses in structured microbial populations

M. Stevanovic, T. Boukéké-Lesplulier, L. Hupe, J. Hasty, P. Bittihn, D. Schultz

Frontiers in Microbiology 13

Local measures enable COVID-19 containment with fewer restrictions due to cooperative effects

P. Bittihn, L. Hupe, J. Isensee, R. Golestanian

EClinicalMedicine (The Lancet) 32, 100718

Arrhythmia mechanism and dynamics in a humanized mouse model of inherited cardiomyopathy due to phospholamban R14del mutation

N. Raad, P. Bittihn, M. Cacheux, D. Jeong, Z. Ilkan, D. Ceholski, E. Kohlbrenner, L. Zhang, C.-L. Cai, E. G. Kranias, R. J. Hajjar, F. Stillitano, F. G. Akar

Circulation 144, 441

Stochastic effects on the dynamics of an epidemic due to population subdivision

P. Bittihn, R. Golestanian

Chaos 30, 101102

Genetically engineered control of phenotypic structure in microbial colonies

P. Bittihn, A. Didovyk, L. S. Tsimring, J. Hasty

Nature Microbiology 5, 697

Divergent aging of isogenic yeast cells revealed through single-cell phenotypic dynamics

M. Jin, Y. Li, R. O'Laughlin, P. Bittihn, L. Pillus, L. S. Tsimring, J. Hasty, N. Hao

Cell Systems 8, 242

Rational engineering of synthetic microbial systems: From single cells to consortia

P. Bittihn, M. O. Din, L. S. Tsimring, J. Hasty

Current Opinion in Microbiology 45, 92

Electromechanical vortex filaments during cardiac fibrillation

J. Christoph, M. Chebbok, C. Richter, J. Schröder-Schetelig, P. Bittihn, S. Stein, I. Uzelac, F. H. Fenton, G. Hasenfuß, R. F. Gilmour Jr., S. Luther

Nature 555, 667

Emergent dynamics of spatio-temporal chaos in a heterogeneous excitable medium

P. Bittihn, S. Berg, U. Parlitz, S. Luther

Chaos 27, 093931

Gene conversion facilitates adaptation on rugged fitness landscapes

P. Bittihn, L. S. Tsimring

Genetics 207, 1577

Suppression of beneficial mutations in dynamic microbial populations

P. Bittihn, J. Hasty, L. S. Tsimring

Physical Review Letters 118, 028102

Multi-generational silencing dynamics control cell aging

Y. Li, M. Jin, R. O'Laughlin, P. Bittihn, L. S. Tsimring, L. Pillus, J. Hasty, N. Hao

PNAS 114, 11253

Complex restitution behavior and reentry in a cardiac tissue model for neonatal mice

A. Mayer, P. Bittihn, S. Luther

Physiological Reports 5, e13449

A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis

S. R. Scott, M. O. Din, P. Bittihn, L. Xiong, L. S. Tsimring, J. Hasty

Nature Microbiology 2, 17083

Scanning and resetting the phase of a pinned spiral wave using periodic far field pulses

T. K. Shajahan, S. Berg, S. Luther, V. Krinski, P. Bittihn

New Journal of Physics 18, 043012

Complex Structure and Dynamics of the Heart

P. Bittihn

Springer International Publishing (Springer Theses), ISBN 978-3-319-12231-1

Requirement analysis for an electronic laboratory notebook for sustainable data management in biomedical research

J. Menzel, P. Weil, P. Bittihn, D. Hornung, N. Mathieu, S. Y. Demiroglu

Studies in Health Technology and Informatics 192, 1108

Negative curvature boundaries as wave emitting sites for the control of biological excitable media

P. Bittihn, M. Hörning, S. Luther

Physical Review Letters 109, 118106

Low-energy control of electrical turbulence in the heart

S. Luther, F. H. Fenton, B. G. Kornreich, A. Squires, P. Bittihn, D. Hornung, M. Zabel, J. Flanders, A. Gladuli, L. Campoy, E. M. Cherry, G. Luther, G. Hasenfuss, V. I. Krinsky, A. Pumir, R. F. Gilmour Jr., E. Bodenschatz

Nature 475, 235

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

S. Petitprez, A. F. Zmoos, J. Ogrodnik, E. Balse, N. Raad, S. El-Haou, M. Albesa, P. Bittihn, S. Luther, S. E. Lehnart, S. N. Hatem, A. Coulombe, H. Abriel

Circulation Research 108

Understanding and predicting the response of pinned vortices to periodic electric far-field stimuli

A. Behrend, P. Bittihn, S. Luther

Biomedical Engineering 55

Predicting unpinning success rates for a pinned spiral in an excitable medium

A. Behrend, P. Bittihn, S. Luther

Computing in Cardiology 37, 345

Fast parallel simulations of excitable media dynamics on multicore processors and graphics processing units

S. Berg, P. Bittihn, S. Luther, U. Parlitz

Proceedings of the 6th ESGCO

Phase-resolved analysis of the susceptibility of pinned spiral waves to far-field pacing in a two-dimensional model of excitable media

P. Bittihn, A. Squires, G. Luther, E. Bodenschatz, V. Krinsky, U. Parlitz, S. Luther

Philosophical Transactions of the Royal Society A 368, 2221

Far field pacing supersedes anti-tachycardia pacing in a generic model of excitable media

P. Bittihn, G. Luther, E. Bodenschatz, V. Krinsky, U. Parlitz, S. Luther

New Journal of Physics 10, 103012

Improving interaction and perception of brain structure using fiber clustering

J. Klein, A. Vilanova, P. Ledochowitsch, P. Bittihn, H. K. Hahn, O. Konrad, J. Rexilius, H.-O. Peitgen

SPIE Newsroom

Grid-based spectral fiber clustering

J. Klein, P. Bittihn, P. Ledochowitsch, H. K. Hahn, O. Konrad, J. Rexilius, H.-O. Peitgen

Proc. SPIE 6509, 65091E